Christina McGuire

Christina McGuire

Company: Guardian Therapeutics

Job title: Senior Scientist


Sharing Aptamer-Drug Conjugates (ApDC’s): Using the “Chemical Antibody” to Target Cancer Biomarkers & Kill Tumor Cells 8:30 am

Identification and optimization of nuclease stable, fully modified 2’OMethyl RNA aptamers that recognize cancer biomarkers with high affinity and specificity through a process called SELEX. A review of the chemical advantages of aptamers over antibodies for developing drug conjugates and the synthesis of aptamer-drug conjugates. Selective in vitro and in vivo killing of cancer cells…Read more

day: Day Two

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