Thomas Smith

Thomas Smith

Company: Novartis AG

Job title: Associate Director - Chemical Biology & Therapeutics


Extracellular Targeted Protein Degradation: An Emerging Therapeutic Modality 9:00 am

• Advancements in Targeted Protein Degradation research shows that targeted removal can now be accomplished external to the classic ligase-ubiquitination pathway found within cells • Novel bispecific antibodies, antibody-conjugates, and bifunctional small molecules can all drive engagement and clearance of extracellular plasma and membrane protein targets • Describing the application of these bifunctional conjugate tools…Read more

day: Scientific Program Day Two

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