Vicky Appleman

Vicky Appleman

Company: Takeda Pharmaceutical Co. Ltd.

Job title: Principal Scientist


Targeting STING to CCR2+ Cells Via an Immune Stimulating Antibody Conjugate 12:00 pm

The murine surrogate ISAC, mTAK-500, was designed to selectively deliver the STING agonist, TAK-676, to CCR2+ cells mTAK-500 enabled the characterization of the exposure, potency, mechanism, and anti-tumor activity of targeting STING to CCR2+ cells CCR2-mediated delivery of TAK-676 triggered dose-dependent activation of the STING signaling pathway, as well as robust activation of innate and…Read more

day: Scientific Program Day One

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