Colby Souders

Company: Brick Bio

Job title: Chief Scientific Officer

Seminars:

Optimizing Site of Conjugation Modulates ADC Efficacy & Reducing Toxicity for Complex Immuno-Oncology Payloads & Formats 2:00 pm

Complex payloads require a site-selective approach to identify optimal conjugates with the widest therapeutic index possible. Finding the right site of conjugation, which varies by payload, can increase the TI by >5-fold via both MED and MTD improvements Unique drug conjugate compositions, such as multi-payload conjugates, benefit from unique and orthogonal chemistries to enable one-pot…Read more

day: Conference Day Two