Colby Souders

Colby Souders

Company: BrickBio

Job title: Chief Scientific Officer


Optimizing Site of Conjugation Modulates ADC Efficacy & Reducing Toxicity for Complex Immuno-Oncology Payloads & Formats 9:00 am

Complex payloads require a site-selective approach to identify optimal conjugates with the widest therapeutic index possible. Finding the right site of conjugation, which varies by payload, can increase the TI by >5-fold via both MED and MTD improvements Unique drug conjugate compositions, such as multi-payload conjugates, benefit from unique and orthogonal chemistries to enable one-pot…Read more

day: Conference Day Two

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