Graham Cotton

Graham Cotton

Company: Almac

Job title: Vice President Protein Therapeutics

Seminars:

Exploiting Novel Protein Domain Architectures to Deliver Next-Generation Bispecific & Biparatopic Protein Drug Conjugates 11:30 am

A suite of protein-drug conjugates (PDCs) have been developed which exploit small protein domain binders to deliver differentiated homogeneous conjugates Lead PDCs targeting ROR1 and ALPP/ALPPL2 have been engineered to provide enhanced delivery of payloads through utilization of bispecific and biparatopic architectures and cause sustained regressions in cancer models in vivo PDC target binders, payloads…Read more

day: Conference Day Two

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